Systemic Lupus Erythematosus (SLE)

What is SLE?

Systemic Lupus Erythematosus, or lupus, is an autoimmune disease, which means the body’s immune system attacks its own healthy tissues. Lupus can affect many parts of the body — including the joints, skin, kidneys, lungs, heart, and brain.

It is more common in women, often starting in the teenage years or early adulthood.

How can I recognize it?

Lupus can look different in different people. Common signs and symptoms include:

• Joint pain and swelling, especially in the hands, wrists, and knees
• Extreme tiredness, even after rest
• A butterfly-shaped rash over the cheeks and nose and rashes that worsen with sunlight
• Hair loss or thinning hair
• Fever, not linked to infection
• Recurrent mouth ulcers (painless or painful)
• Swelling in the legs or puffiness around the eyes (can be a sign of kidney involvement)
• Chest pain when taking a deep breath
• Headaches, memory problems, or confusion